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Louis Cardinals, the defending World Series champions, at home in San Francisco, after winning Game 7 of the National League Championship Series.
In accordance with the standard since 2003, the outcome of the All-Star Game decided whether the American or National League would hold home field advantage in the World Series.
The San Francisco Giants, the National League champions, won the best-of-seven playoff in a 4-game sweep over the American League champions Detroit Tigers.
This marked the Giants' seventh World Series title in franchise history, their second in San Francisco (they won five in New York), and their second in a three-year period (2010–2012).
The last time, before 2011–2012, that the Tigers franchise had made consecutive playoff appearances was 1934–1935.
The Tigers defeated the Oakland Athletics in the American League Division Series three games to two.
The San Francisco Giants held home field advantage for the best-of-seven World Series: San Francisco hosted Games 1 and 2, and would have hosted Games 6 and 7 if these had been necessary to decide the Series.
The 2012 series began on Wednesday, October 24, at AT&T Park in San Francisco, California and ended on Sunday, October 28, at Comerica Park in Detroit, Michigan, with the conclusion of the fourth game.
The Giants' Pablo Sandoval, who in Game 1 tied a record by hitting three home runs in one World Series game, two off of Tigers' ace Justin Verlander, was named the World Series Most Valuable Player (MVP).
The Giants lost the first two games at home in San Francisco, yet won the last three on the road.
The Giants became the first major league team to win three straight road games in a best-of-five playoff series after losing the first two games at home.
Bruce Bochy made his third World Series appearance as a manager, his second with the Giants. Before that, he led the 1998 San Diego Padres to the World Series, where the New York Yankees swept. Bochy's starting rotation for the 2012 World Series: Barry Zito in Game 1, Madison Bumgarner in Game 2, Ryan Vogelsong in Game 3 and Matt Cain in Game 4.
The Tigers finished the regular season atop the American League Central, with 88 wins and 74 losses.