Adult sex dating in cushing nebraska

Delay to diagnosis was considered as the time from symptom onset (in months) to the date of diagnosis of CS.Both patients and controls performed a battery of neuropsychological tests related to cerebellar functions.Recently, the cerebellum has been related to emotional control and cognition, and linked to frontal/executive functions, visuospacial skills, visual memory, verbal working memory, declarative and procedural memory, information processing speed, language, fluency, and emotional processing (21, 22, 23).

Whole brain and hippocampal atrophy and neuropsychological dysfunction have been described in CS, but consensus is lacking about the reversibility of the effects of cortisol on the brain after biochemical control (6, 7, 8, 9, 16, 17, 18, 19).This finding is associated with poor visual memory and quality of life and is mostly pronounced in patients with higher triglyceride levels and older age at diagnosis.Cushing's syndrome (CS) is a rare disease caused by chronic glucocorticoid excess.Chronic exposure to excess glucocorticoids can exert a neurotoxic effect (10, 11).In CS, this has been specifically associated with aging-like effects on the brain (12).

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